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Tilted-grating approach for scanning-mode X-ray phase contrast imaging

机译:倾斜光栅方法用于扫描模式X射线相衬成像

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摘要

Among the existent X-ray phase-contrast modalities, grating interferometry appears as a very promising technique for commercial applications, since it is compatible with conventional X-ray tubes and is robust from a mechanical point of view. However, since applications such as medical imaging and homeland security demand covering a considerable field of view, the fabrication of large-area gratings, which is known to be challenging and expensive, would be needed. A scanning setup is a good solution for this issue, because it uses cheaper line instead of large-area 2D detectors and, therefore, would require smaller gratings. In such a setup, the phase-retrieval using the conventional phase-stepping approach would be very slow, so having a faster method to record the signals becomes fundamental. To tackle this problem, we present a scanning-mode grating interferometer design, in which a grating is tilted to form Moiré fringes perpendicular to the grating lines. The sample is then translated along the fringes, so each line detector records a different phase step for each slice of the sample. This new approach was tested both in a simulated scenario and in an experimental setting, and its performance was quantitatively satisfactory compared to the traditional phase-stepping method and another existing scanning-mode technique.
机译:在现有的X射线相衬模态中,光栅干涉测量法是一种非常有前途的商业应用技术,因为它与常规X射线管兼容并且从机械角度来看是坚固的。然而,由于诸如医学成像和国土安全之类的应用需要覆盖相当大的视野,因此将需要制造已知具有挑战性且昂贵的大面积光栅。扫描设置是解决此问题的好方法,因为它使用便宜的线代替大面积的2D检测器,因此需要较小的光栅。在这样的设置中,使用常规相位步进方法的相位检索将非常慢,因此拥有一种更快的记录信号的方法就变得至关重要。为了解决这个问题,我们提出了一种扫描模式光栅干涉仪设计,其中倾斜光栅以形成垂直于光栅线的莫尔条纹。然后,样本将沿着边缘平移,因此每个线检测器针对样本的每个切片记录一个不同的相位步长。与传统的相位步进方法和另一种现有的扫描模式技术相比,该新方法已经在模拟场景和实验环境中进行了测试,其性能在数量上令人满意。

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